EUROIMMUN ELISAs are globally recognized as some of the most reliable and versatile immunoassays in laboratory diagnostics. They provide both quantitative and semiquantitative determination of antibodies and antigens, delivering accurate and reproducible results across a broad spectrum of disease areas. In the Caribbean, EUROIMMUN ELISAs are available exclusively through Southern Medical Supplies Limited, ensuring laboratories gain access to world-class assays with local support and expertise.
At the core of EUROIMMUN ELISA technology is the enzyme-linked immunosorbent assay principle, which uses antigens or antibodies coated on 96-well polystyrene plates as a solid phase. Patient samples are incubated with these reagents, and specific binding events are detected by means of an enzymatic color reaction. The intensity of the resulting color solution is directly or inversely proportional to the concentration of the analyte being measured, depending on the assay format. This simple yet powerful principle allows for a wide range of applications in autoimmunity, infectious diseases, antigen detection, allergy diagnostics, and therapeutic drug monitoring (TDM).
A major strength of EUROIMMUN ELISAs lies in their comprehensive product portfolio. The range covers autoimmune diagnostics such as celiac disease, autoimmune hepatitis, diabetes, and systemic autoimmune syndromes; infectious disease testing for bacterial, viral, and parasitic pathogens; antigen detection assays; allergy testing; and specialized parameters for therapeutic monitoring. This breadth ensures that laboratories can build a consistent, standardized workflow across all disease areas while relying on the same trusted technology.
EUROIMMUN’s in-house antigen design and production guarantees the highest test quality, with reagents optimized for specificity and reproducibility. Test kits are supplied with all necessary reagents included, reducing the need for additional consumables. Each reagent is barcoded and color-coded, ensuring secure handling in both manual and automated workflows. The use of universal incubation schemes across different kits simplifies combined processing of multiple parameters on the same run, further enhancing laboratory efficiency.
Automation is a key advantage of EUROIMMUN ELISAs, allowing laboratories to scale operations without sacrificing accuracy. The assays are optimized for use on fully automated systems such as the EUROLabWorkstation ELISA, the EUROIMMUN Analyzer I, and the EUROIMMUN Analyzer I-2P, as well as the versatile Sprinter XL. These instruments cover every throughput need, from small hospital labs to national reference centers, and integrate seamlessly with laboratory information systems (LIS) via EUROLabOffice 4.0 middleware for complete traceability and reporting.
In antibody detection assays, the antigen-coated wells of the microplate are incubated with diluted patient samples. If antibodies against the antigen are present, they bind specifically. A peroxidase-labelled conjugate is then added, binding to the patient antibodies. Finally, tetramethylbenzidine (TMB) substrate is introduced, and the peroxidase catalyzes a color reaction. The intensity of the color is proportional to the antibody concentration and can be measured against a calibration curve for quantitative results, or expressed as a ratio for semiquantitative detection.
Competitive antibody ELISAs work on a slightly different principle. Patient antibodies compete with a biotin-labelled artificial molecule for binding sites on the coated antigen. A peroxidase-labelled avidin conjugate is then introduced, which binds the biotin-labelled molecules. The final TMB reaction produces a color intensity that is inversely proportional to the antibody concentration in the sample, allowing precise quantification.
For antigen detection, sandwich ELISAs are used. Wells are coated with monospecific antibodies that bind to the target antigen in the patient sample. A second peroxidase-labelled antibody binds to another epitope of the same antigen, creating a “sandwich.” Upon addition of TMB, a color reaction occurs, with intensity directly proportional to the antigen concentration.
In competitive antigen ELISAs, patient antigens compete with a biotin-labelled antigen for binding sites on the antibody-coated wells. Peroxidase-labelled streptavidin binds the biotin-labelled antigen, and the final TMB color reaction is inversely proportional to the antigen concentration in the sample. Both approaches allow precise measurement and are tailored for different diagnostic needs.
EUROIMMUN also offers profile ELISAs, which allow the semiquantitative detection of multiple antibodies on a single microplate strip. These assays use antigen mixtures coated on wells to screen for groups of antibodies, with subsequent confirmation performed using monospecific assays for full diagnostic clarity.
EUROIMMUN ELISAs combine comprehensive diagnostic coverage with ease of use, automation readiness, and robust test quality. Laboratories benefit from assays that are designed to reduce manual errors, standardize workflows, and deliver reproducible results. With barcoded, ready-to-use reagents, universal incubation schemes, and compatibility with EUROIMMUN’s full suite of automated processors, these ELISAs set the gold standard for modern immunodiagnostics.
For laboratories in the Caribbean, the benefits of EUROIMMUN ELISAs are supported by Southern Medical Supplies Limited, which provides not only access to the full portfolio but also training, technical support, and service to ensure successful implementation. This partnership guarantees that laboratories achieve world-class standards in antibody and antigen testing while operating with the confidence of local expertise.
EUROIMMUN ELISAs represent a complete solution for laboratories that value accuracy, efficiency, and diagnostic breadth. From small-scale manual testing to fully automated, high-throughput workflows, EUROIMMUN provides the flexibility and reliability to meet today’s growing diagnostic demands.
👉 Available now from Southern Medical Supplies Limited — your trusted partner for EUROIMMUN ELISA diagnostics and automation in the Caribbean
With over three decades of regional expertise, SMSL is more than a supplier—we are your partner in healthcare innovation. By combining trusted global brands with unmatched local support, we deliver solutions that improve outcomes, reduce risks, and empower healthcare professionals to perform at their very best.
