Autoimmune dermatoses—including pemphigus vulgaris/foliaceus, bullous pemphigoid, linear IgA disease, epidermolysis bullosa acquisita, dermatitis herpetiformis, cutaneous lupus, and dermatomyositis—require integrated serology and immunofluorescence to pinpoint target antigens and split level. At Southern Medical Supplies Limited (SMSL), we support a complete workflow: IIF/BIOCHIP® mosaics on monkey esophagus and salt-split human skin (roof vs floor localization), ELISAs for anti-desmoglein-1/3, BP180 (NC16A), BP230, type VII collagen, envoplakin/periplakin, direct immunofluorescence (DIF) reagents for perilesional skin (IgG/IgA/C3), adjunct celiac serologies (tTG-IgA, EMA, DGP) for dermatitis herpetiformis, and complementary myositis/ENA panels when systemic disease is suspected. Our portfolio spans ELISA, immunoblot, immunofluorescence, molecular, and clinical chemistry platforms sourced from a broad network of trusted partners—EUROIMMUN, Ansh Labs, Randox, Streck, Bio-Rad, Abbott, Roche, Siemens Healthineers, Qiagen, bioMérieux, Cepheid, Werfen, Globe Scientific, ELGA LabWater, LW Scientific, Sebia, LTA SRL, Acrobiotech, MAKOL Innovacion Medica, Rayto Life and Analytical Sciences, Diazyme, Hardy’s Diagnostics, and Teco Diagnostics—delivering the sensitivity, specificity, and reproducibility clinicians need to confirm diagnosis, monitor activity, and guide therapy in autoimmune skin disease.