Abacavir hypersensitivity is strongly associated with the HLA-B*57:01 allele; screening before therapy initiation is the standard of care to prevent potentially life-threatening reactions. At Southern Medical Supplies Limited (SMSL), we provide HLA-B*57:01 genotyping from EDTA whole blood or buccal swab using validated qPCR/allele-specific PCR or NGS/sequence-based typing, with optional reflex confirmation and clear clinical interpretation (positive → avoid abacavir; negative → markedly reduced risk). Our end-to-end solution includes pre-analytical kits, controls, and reporting aligned to international guidance, leveraging platforms and consumables from our broad network of partners—EUROIMMUN, Ansh Labs, Randox, Streck, Bio-Rad, Abbott, Roche, Siemens Healthineers, Qiagen, bioMérieux, Cepheid, Werfen, Globe Scientific, ELGA LabWater, LW Scientific, Sebia, LTA SRL, Acrobiotech, MAKOL Innovacion Medica, Rayto Life and Analytical Sciences, Diazyme, Hardy’s Diagnostics, and Teco Diagnostics—to ensure accuracy, traceability, and reproducibility in abacavir sensitivity testing.
